Enhanced membrane protein expression by engineering increased intracellular membrane production

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Enhanced membrane protein expression by engineering increased intracellular membrane production

BACKGROUND Membrane protein research is frequently hampered by the low natural abundance of these proteins in cells and typically relies on recombinant gene expression. Different expression systems, like mammalian cells, insect cells, bacteria and yeast are being used, but very few research efforts have been directed towards specific host cell customization for enhanced expression of membrane p...

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ژورنال

عنوان ژورنال: Microbial Cell Factories

سال: 2013

ISSN: 1475-2859

DOI: 10.1186/1475-2859-12-122